Flu Vaccine Technology

Flu shot then and now

History of the flu virus and influenza vaccination

References: 1. US Department of Health and Human Services. The pandemic. http://www.flu.gov/pandemic/history/1918/the_pandemic/index.html. Accessed July 20, 2015. 2. Artenstein AW, Opal JM, Opal SM, Tramont EC, Peter G, Russell PK. History of U.S. military contributions to the study of vaccines against infectious diseases. Mil Med.
2005;170(suppl 4):3-11. 3. DuBois LA. Ernest Goodpasture and the mass production of vaccines. Vanderbilt Medical Center website. http://www.mc.vanderbilt.edu/lens/article/?id=92&pg=999. Published April 2004. Accessed July 20, 2015. 4. Francis T Jr. Vaccination against influenza. Bull World Health Organ. 1953;8(5-6):725-741. 5. Andrewes CH. Influenza: theme and variations. Calif Med. 1956;84(6):375-380. 6. Human cell strains in vaccine development. The College of Physicians of Philadelphia website. http://www.historyofvaccines.org/content/articles/human-cell-strains-vaccine-development. Accessed July 20, 2015. 7. US Food and Drug Administration. Summary minutes: Vaccines and Related Biological Products Advisory Committee: Meeting #104: November 16-17, 2005. http://www.fda.gov/ohrms/dockets/ac/05/minutes/2005-4188m1.pdf. Accessed July 20, 2015. 8. FLUCELVAX (Influenza Vaccine) [package insert]. Holly Springs, NC: Seqirus Inc; 2015. 9. US Food and Drug Administration. FDA approves first seasonal influenza vaccine manufactured using cell culture technology. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm328982.htm. Updated 2012. Accessed September 9, 2015. 10. A milestone in protection from influenza. US Department of Health and Human Services website. http://www.hhs.gov/news/press/2014pres/06/20140617a.html. Accessed July 20, 2015. 11. FLUCELVAX QUADRIVALENT [package insert]. Holly Springs, NC: Seqirus Inc; 2016.

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IMPORTANT SAFETY INFORMATION

What is FLUCELVAX QUADRIVALENT® (Influenza Vaccine)?

FLUCELVAX QUADRIVALENT is a vaccine that helps protect against influenza (flu). FLUCELVAX is for people aged 4 and older. Vaccination with FLUCELVAX QUADRIVALENT may not protect all people who receive the vaccine.

Who should not get FLUCELVAX QUADRIVALENT?

You should not get FLUCELVAX QUADRIVALENT if you have had a severe allergic reaction to any of the ingredients in the vaccine.

IMPORTANT SAFETY INFORMATION

What is FLUCELVAX QUADRIVALENT® (Influenza Vaccine)?

FLUCELVAX QUADRIVALENT is a vaccine that helps protect against influenza (flu). FLUCELVAX is for people aged 4 and older. Vaccination with FLUCELVAX QUADRIVALENT may not protect all people who receive the vaccine.

Who should not get FLUCELVAX QUADRIVALENT?

You should not get FLUCELVAX QUADRIVALENT if you have had a severe allergic reaction to any of the ingredients in the vaccine.

Who may not be able to get FLUCELVAX QUADRIVALENT?

Tell your healthcare provider if you:

  • have ever had Guillain-Barré Syndrome (severe muscle weakness) after getting a flu shot
  • have ever fainted after receiving an injection

What if I have a weakened immune system?

Tell your healthcare provider if you have problems with your immune system, as your immune response to the vaccine may be less.

What are the most common side effects of FLUCELVAX QUADRIVALENT?

  • pain or redness where you got the shot
  • headache
  • tiredness
  • muscle aches
  • feeling unwell (malaise)

These are not all of the possible side effects of FLUCELVAX QUADRIVALENT. You can ask your healthcare provider for a complete list of possible side effects.

Ask your healthcare provider for advice about any side effects that concern you. You may report side effects to the Vaccine Adverse Events Reporting System (VAERS) by calling 1-800-822-7967 or by going to http://vaers.hhs.gov.

To report SUSPECTED ADVERSE REACTIONS, contact Seqirus at 1-855-358-8966 or VAERS at 1-800-822-7967 and http://vaers.hhs.gov.

Please see accompanying US full Prescribing Information for FLUCELVAX QUADRIVALENT.